Pathogenesis of Feline Panleukopenia Virus in Susceptible Newborn Kittens II. Pathology and Immunofluorescence
نویسندگان
چکیده
منابع مشابه
Pathogenesis of feline panleukopenia virus in susceptible newborn kittens I. Clinical signs, hematology, serology, and virology.
Inoculation of susceptible newborn kittens with a large dose of panleukopenia virus caused subclinical infection in 19 of 23 cases. All infected kittens developed severe and prolonged leukopenia. Cell-free virus was present in the blood from 1 to 7 postinoculation days. The virus spread to all organs, regardless of the route of inoculation. The thymus, spleen, mesenteric lymph nodes, and the ce...
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BACKGROUND Feline Panleukopenia (FPL) is a serious disease of cats that can be prevented by vaccination. Kittens are routinely vaccinated repeatedly during their first months of life. By this time maternally derived antibodies (MDA) can interfere with vaccination and inhibit the development of active immunity. The efficacy of primary vaccination under field conditions was questioned by frequent...
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Introduction Feline panleukopenia is caused by feline parvovirus (FPV), which is a highly contagious virus affecting all members of Felidae. Severity of clinical signs depends on age, immune status, and concurrent infections. Clinical disease ranges from subclinical infection to a peracute syndrome with sudden death. Typical initial signs include fever, depression, and anorexia. Affected cats c...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1971
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.3.6.838-846.1971